| 克隆類型 ： |
Mouse Monoclonal Antibody |
|
亞 型 ： |
Mouse IgG1 |
|
免 疫 原 ： |
Thyroglobulin-conjugated synthetic peptide encompassing a sequence within the N-term region of human Blcl-2. |
|
產(chǎn)品描述 ： |
Apoptosis regulator Bcl-2 (Bcl-2) suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Bcl-2 regulates cell death by controlling mitochondrial membrane permeability. Bcl-2 functions in a feedback loop system with caspases, inhibiting caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). A chromosomal aberration involving Bcl-2 has been found in chronic lymphatic leukemia. |
| 適用物種 ： |
H |
|
應用范圍 ： |
E, WB, IHC; ICC |
| 應用說明 ： |
E: 1:500-1:1,000; WB: 1:50-1:200; IHC: 1:100-1:250; ICC: 1:100-1:250 |
| 別 名 ： |
Apoptosis regulator Bcl-2; BCL2 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
產(chǎn)品文獻 ： |
Wu Q et al. 2011. Journal of Ethnopharmacology. 38(1):34-39. PMID# 21856397. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/bcl-2-antibody-0 |
| 標 記 物 ： |
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產(chǎn)品說明 ： |
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