| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human LYVE-1. |
|
產(chǎn)品描述 ： |
Lymphatic vessel endothelial hyaluronic acid receptor 1 (LYVE-1) is a ligand-specific transporter trafficking between intracellular organelles and the plasma membrane. LYVE-1 is involved in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). LYVE-1 acts as a hyaluronan transporter either by mediating its uptake for catabolism within lymphatic endothelial cells or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes. LYVE-1 is localized to the plasma membrane and in vesicles near extranuclear membranes mainly in endothelial cells lining lymphatic vessels. |
| 適用物種 ： |
H, M, R |
|
應(yīng)用范圍 ： |
E, WB, IHC |
| 應(yīng)用說明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 別 名 ： |
LYVE-1; Lymphatic vessel endothelial hyaluronic acid receptor 1; Cell surface retention sequence-binding protein 1; CRSBP-1; Hyaluronic acid receptor; Extracellular link domain-containing protein 1; LYVE1; CRSBP1; HAR; XLKD1 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
產(chǎn)品文獻(xiàn) ： |
Delaloye et al. 2014. Oncoimmunology. 3:e29080. ecollection. PMID#25101222. Bone marrow-derived cells are implicated as a source of lymphatic endothelial progenitors in human breast cancer. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/lyve-1-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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