| 克隆類(lèi)型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human integrin alpha-V/beta-3. |
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產(chǎn)品描述 ： |
Integrin alpha-V/beta-3, also called vitronectin receptor or CD51/CD61, belongs to the integrin protein family that participates in cell adhesion and cell-surface mediated signalling by forming heterodimers of alpha and beta integrin chains. Integrin alpha-V/beta-3 is a receptor for cytoactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrins recognize the sequence RGD in a wide array of ligands. Defects in CD61 are a cause of Glanzmann thrombasthenia, a blot clot disorder. |
| 適用物種 ： |
H, M, R, P, Rb |
|
應(yīng)用范圍 ： |
E, IHC, FC |
| 應(yīng)用說(shuō)明 ： |
E: 1:500-1:1,000; IHC: 1:100-1:500; FC: 1:20-1:100 |
| 別 名 ： |
Vitronectin receptor; Integrin alpha-V; Vitronectin receptor subunit alpha; CD51; Integrin beta-3; Platelet membrane glycoprotein IIIa; GPIIIa; CD61; ITGB3; GP3A |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
產(chǎn)品文獻(xiàn) ： |
[1] Panth KM et al. 2016. Sci Rep. 6: 22198. PMID 26923459. [2] Crisp J. et al. 2014. Mol Cancer Ther. PMID 24737028. [3] Du Y. et al. 2012. PLoS ONE. 7(9):e43941. PMID# 23049742. [4] Gao S. et al. 20 |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/integrin-alpha-v-beta-3-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說(shuō)明 ： |
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