克隆類(lèi)型 : |
Rabbit Polyclonal Antibody |
亞 型 : |
Rabbit Ig |
免 疫 原 : |
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CFTR. |
產(chǎn)品描述 : |
Cystic fibrosis transmembrane conductance regulator (CFTR), a ABC transporter, is involved in the transport of chloride ions and regulates bicarbonate secretion in epithelial cells by regulating the SLC4A7 transporter. CFTR is localized in aggresome bodies when proteasome's degradative capacity is exceeded and lysosomal degradation is engaged via autophagy. Defects in CFTR are the cause of cystic fibrosis. |
適用物種 : |
H, M, R, B, D |
應(yīng)用范圍 : |
E, WB, IHC |
應(yīng)用說(shuō)明 : |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
別 名 : |
CFTR; Cystic fibrosis transmembrane conductance regulator; Channel conductance-controlling ATPase; cAMP-dependent chloride channel; ATP-binding cassette transporter sub-family C member 7; ABCC7 |
形 態(tài) : |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
保存條件 : |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
產(chǎn)品鏈接 : |
http://www.abbiotec.com/antibodies/cftr-antibody-0 |
標(biāo) 記 物 : |
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產(chǎn)品說(shuō)明 : |
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