| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human protein API-5 . |
|
產品描述 ： |
Apoptosis inhibitor 5 (API-5) is an antiapoptotic factor that plays a role in protein assembly. API-5 negatively regulates ACIN1. By binding to ACIN1, API-5 suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. API-5 also efficiently suppresses E2F1-induced apoptosis. Low levels of API-5 enhance the cytotoxic action of the chemotherapeutic drugs. |
| 適用物種 ： |
H, M, R |
|
應用范圍 ： |
E, WB, IHC, IP |
| 應用說明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IP: 1:100-1:500 |
| 別 名 ： |
API-5; Apoptosis inhibitor 5; Fibroblast growth factor 2-interacting factor; FIF; Protein XAGL; Antiapoptosis clone 11 protein; AAC-11; Cell migration-inducing gene 8 protein; API5; MIG8 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產品鏈接 ： |
http://www.abbiotec.com/antibodies/api-5-antibody |
| 標 記 物 ： |
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產品說明 ： |
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