| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ADRB2. |
|
產(chǎn)品描述 ： |
The beta-2 adrenergic receptor is a G-protein coupled adrenergic receptor with 30-fold higher affinity for epinephrine than norepinephrine. Agonist binding to the beta-2 adrenergic receptor initiates signal transduction pathways via activation of adenylyl cyclases. There are numerous physiological effects of beta-2 adrenergic receptor activation, including smooth muscle relaxation, blood vessel dilation, increased heart rate, and insulin secretion. The Gly-16 allele is overrepresented in individuals affected by nocturnal asthma as compared to controls, and appears to be an important genetic factor in the expression of this asthmatic phenotype. |
| 適用物種 ： |
H, M, R, Ch, Mk, GP, D |
|
應(yīng)用范圍 ： |
E, WB, IHC |
| 應(yīng)用說明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 別 名 ： |
ADRB2; Beta-2 adrenergic receptor; Beta-2 adrenoreceptor; Beta-2 adrenoceptor; ADRB2R; B2AR |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
產(chǎn)品文獻(xiàn) ： |
Stiles J et al. 2013. PLoS ONE. 8(3):e60021. PMID# 23555867. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/adrb2-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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