| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Beta-ARK-1. |
|
產品描述 ： |
Beta-adrenergic receptor kinase 1 (Beta-ARK-1) specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Beta-ARK-1 is a key regulator of LPAR1 signaling. Beta-ARK-1 competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Beta-ARK-1 desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner. Beta-ARK-1 is expressed in peripheral blood leukocytes. |
| 適用物種 ： |
H, M, R |
|
應用范圍 ： |
E, WB, IHC |
| 應用說明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 別 名 ： |
Beta-ARK-1; Beta-adrenergic receptor kinase 1; G-protein coupled receptor kinase 2; GRK2; ADRBK1; BARK; BARK1 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產品鏈接 ： |
http://www.abbiotec.com/antibodies/beta-ark-1-antibody |
| 標 記 物 ： |
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產品說明 ： |
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