| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of mouse caspase-12. |
|
產(chǎn)品描述 ： |
Inactive caspase-12 (caspase-12) reduces cytokine release in response to bacterial lipopolysaccharide during infections. Caspase-12 reduces reduces activation of NF-kappa-B in response to TNF. Caspase-12 does not have protease activity. The most frequent caspase-12 variant has a stop codon instead of Arg-125, giving rise to a truncated protein (Csp12-S). The variant Arg-125 (Csp12-L) is rare, except in some populations from sub-Saharan Africa. Csp12-L may increase the susceptibility to severy sepsis, and may also increase the mortality rate in sepsis patients.
|
| 適用物種 ： |
M, R |
|
應(yīng)用范圍 ： |
E, WB, IHC, IP |
| 應(yīng)用說(shuō)明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500; IP: 1:100-1:500 |
| 別 名 ： |
Caspase-12; Inactive caspase-12; CASP12; CASP-12 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/caspase-12%C2%A0-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說(shuō)明 ： |
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