| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Skp2. |
|
產(chǎn)品描述 ： |
Skp2 (S-phase kinase-associated protein 2) is a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Skp2 specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. |
| 適用物種 ： |
H, M, R |
|
應(yīng)用范圍 ： |
E, WB, IHC |
| 應(yīng)用說明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 別 名 ： |
Skp2; S-phase kinase-associated protein 2; F-box protein Skp2; Cyclin A/CDK2-associated protein p45; p45skp2; F-box/LRR-repeat protein 1; FBXL1 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
產(chǎn)品文獻(xiàn) ： |
Pushpavalli S et al. 2011. Cancer Cell Int. 11:36. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/skp2-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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