| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CD184. |
|
產(chǎn)品描述 ： |
C-X-C chemokine receptor type 4 (CXCR-4, CD184) is a receptor for the C-X-C chemokine CXCL12 (SDF-1) that transduces a signal by increasing intracellular calcium ions levels and enhancing MAPK1/MAPK3 activation. CD184 also acts as a receptor for extracellular ubiquitin. CD184 is involved in haemostasis, in cardiac ventricular septum formation and acts as a coreceptor with CD4 for HIV-1 isolates. Defects in CD184 are a cause of WHIM syndrome (warts, hypogammaglobulinemia, infections and myelokathexis). |
| 適用物種 ： |
H, M, R |
|
應(yīng)用范圍 ： |
E, WB, IHC |
| 應(yīng)用說明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 別 名 ： |
CXC-R4; CD184; C-X-C chemokine receptor type 4; CXCR-4; Stromal cell-derived factor 1 receptor; SDF-1 receptor; Fusin; Leukocyte-derived seven transmembrane domain receptor; LESTR; LCR1; FB22; NPYRL; HM89 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/cd184-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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