| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of mouse PDX-1. |
|
產(chǎn)品描述 ： |
Pancreas/duodenum homeobox protein 1 (PDX-1) activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. PDX-1 is particularly involved in glucose-dependent regulation of insulin gene transcription. PDX-1 binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, PDX-1 specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At the adult stage, PDX-1 is required for maintaining the hormone-producing phenotype of the beta-cell. |
| 適用物種 ： |
H, M, R, P, Ck |
|
應用范圍 ： |
E, WB, IHC |
| 應用說明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 別 名 ： |
PDX-1; Pancreatic and duodenal homeobox 1; Pancreas/duodenum homeobox 1; Insulin promoter factor 1; IPF-1; Islet/duodenum homeobox-1; IDX-1; Somatostatin-transactivating factor 1; STF-1; Insulin upstream factor 1; IUF-1; Glucose-sensitive factor; GSF; PDX1; IPF1 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/pdx-1-antibody |
| 標 記 物 ： |
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產(chǎn)品說明 ： |
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