| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human BK Channel. |
|
產(chǎn)品描述 ： |
The BK channel (calcium-activated potassium channel subunit alpha-1 or KCNMA1) is a potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). BK channel is also activated by the concentration of cytosolic Mg(2+). BK channel has a key role in controlling excitability in a numerous systems, such as smooth muscle contraction, tuning of hair cells in the cochlea, regulation of transmitter release, and innate immunity. Defects in KCNMA1 are the cause of generalized epilepsy and paroxysmal dyskinesia (GEPD). |
| 適用物種 ： |
H, M, R, Rb, Sh, B, D, Ck, Zf, Ds |
|
應(yīng)用范圍 ： |
E, WB, IHC |
| 應(yīng)用說明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 別 名 ： |
Calcium-activated potassium channel subunit alpha-1; Calcium-activated potassium channel, subfamily M subunit alpha-1; Maxi K channel; MaxiK; BK channel; K(VCA)alpha; BKCa channel; BKCA alpha; KCa1.1; Slowpoke homolog; slo homolog; Slo-alpha; Slo1; hSlo; KCNMA1; KCNMA; SLO |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
產(chǎn)品文獻(xiàn) ： |
Wan XJ et al. 2015. Int J Biochem Cell Biol. PMID 25481230. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/bk-channel-c-term-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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