| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the leucine zipper region of human c-Myc. |
|
產(chǎn)品描述 ： |
The Myc proto-oncogene protein (c-Myc) participates in the regulation of gene transcription. C-Myc is a transcription factor that binds DNA containing the core sequence 5'-CACGATG-3' but also in a non-specific manner. c-Myc activates genes related to cell growth. Overexpression of c-Myc is implicated in the etiology of a variety of hematopoietic tumors. A chromosomal aberration involving MYC is a cause of a B-cell chronic lymphocytic leukemia. This antibody recognizes the C-term c-Myc peptide (EQKLISEEDL) used to express c-Myc-tagged fusion proteins. |
| 適用物種 ： |
H |
|
應用范圍 ： |
E, WB, IHC |
| 應用說明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 別 名 ： |
c-Myc; Myc proto-oncogene protein; transcription factor p64; MYC; Myc Tag; C-Myc Tag |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
產(chǎn)品文獻 ： |
[1] Wu Q et al. 2018. Mol Med Rep. 17(2): 2493-2500. PMID 29207109. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/c-myc-antibody |
| 標 記 物 ： |
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產(chǎn)品說明 ： |
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