克隆類(lèi)型 : |
Rabbit Polyclonal Antibody |
亞 型 : |
Rabbit Ig |
免 疫 原 : |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of mouse ECM1. |
產(chǎn)品描述 : |
Extracellular matrix protein 1 (ECM1) is involved in endochondral bone formation as a negative regulator of bone mineralization. ECM1 stimulates the proliferation of endothelial cells and promotes angiogenesis. ECM1 inhibits MMP9 proteolytic activity. Defects in ECM1 are the cause of lipoid proteinosis (LiP), also known as lipoid proteinosis of Urbach and Wiethe or hyalinosis cutis et mucosae. LiP is a rare autosomal recessive disorder characterized by generalized thickening of skin, mucosae and certain viscera. ECM1 is expressed in breast cancer tissues. Little or no expression is observed in normal breast tissues. |
適用物種 : |
H, M, R |
應(yīng)用范圍 : |
E, WB, IHC |
應(yīng)用說(shuō)明 : |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
別 名 : |
ECM1; Extracellular matrix protein 1; Secretory component p85 |
形 態(tài) : |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1 mg/ml BSA, 25% glycerol with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
保存條件 : |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
產(chǎn)品鏈接 : |
http://www.abbiotec.com/antibodies/ecm1-antibody |
標(biāo) 記 物 : |
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產(chǎn)品說(shuō)明 : |
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