| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human DCC. |
|
產(chǎn)品描述 ： |
Netrin receptor DCC (DCC) is a receptor for netrin, which is required for axon guidance. DCC mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. DCC also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Defects in DCC are the cause of congenital mirror movements Mirror movements are contralateral involuntary movements that mirror voluntary ones. While mirror movements are occasionally found in young children, persistence beyond the age of 10 is abnormal. Mirror movements occur more commonly in the upper extremities. |
| 適用物種 ： |
H, M, R |
|
應(yīng)用范圍 ： |
E, WB, IHC |
| 應(yīng)用說明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 別 名 ： |
DCC; Deleted in colorectal cancer gene; Deleted in colorectal cancer; Netrin receptor DCC; Tumor suppressor protein DCC; Colorectal cancer suppressor; Immunoglobulin superfamily DCC subclass member 1; IGDCC1 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 5 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/dcc-antibody |
| 標 記 物 ： |
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產(chǎn)品說明 ： |
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