克隆類型 : |
Rabbit Polyclonal Antibody |
亞 型 : |
Rabbit Ig |
免 疫 原 : |
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human endostatin. |
產(chǎn)品描述 : |
Collagen alpha-1(XVIII) chain (endostatin) plays a major role in determining the retinal structure as well as in the closure of the neural tube. Endostatin potently inhibits endothelial cell proliferation and angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling. Defects in endostatin are a cause of Knobloch syndrome (KNO). KNO is an autosomal recessive disorder defined by the occurrence of high myopia, vitreoretinal degeneration with retinal detachment, macular abnormalities and occipital encephalocele. |
適用物種 : |
H, M, R |
應(yīng)用范圍 : |
E, WB, IHC |
應(yīng)用說明 : |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
別 名 : |
Endostatin; Collagen alpha-1(XVIII) chain; COL18A1 |
形 態(tài) : |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
保存條件 : |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
產(chǎn)品鏈接 : |
http://www.abbiotec.com/antibodies/endostatin-antibody-0 |
標(biāo) 記 物 : |
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產(chǎn)品說明 : |
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