| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of mouse p19ARF. |
|
產(chǎn)品描述 ： |
P19ARF (Cyclin-dependent kinase inhibitor 2A) induces cell cycle arret in G1 and G2 phases. p19ARF binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestration in the nucleolus. p19ARF also induces G2 arrest and apoptosis in a p53-independent manner by preventing the activation of cyclin B1/CDC2 complexes. |
| 適用物種 ： |
H, M, R |
|
應用范圍 ： |
E, WB, IHC |
| 應用說明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 別 名 ： |
Cyclin-dependent kinase inhibitor 2A; Cyclin-dependent kinase 4 inhibitor A; CDK4I; p16-INK4a; p16-INK4; Cdkn2a; P16ink4a; p14ARF; p19ARF; MLM; CDKN2 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/p19arf-antibody |
| 標 記 物 ： |
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產(chǎn)品說明 ： |
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