| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human CD44. |
|
產(chǎn)品描述 ： |
CD44 antigen (CD44) is a receptor for hyaluronic acid (HA). CD44 mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). The adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. CD44 is responsible for the Indian blood group system. The molecular basis of the In(A)=In1/In(B)=In2 blood group antigens is a single variation in position 46; In(B), the most frequent allele, has Arg-46. |
| 適用物種 ： |
H, M, R |
|
應(yīng)用范圍 ： |
E, WB, IHC |
| 應(yīng)用說明 ： |
E: 1:1,000-1:5,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 別 名 ： |
CD44; CD44 antigen; Phagocytic glycoprotein I; PGP-I; HUTCH-I; Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; Hermes antigen; Hyaluronate receptor; Heparan sulfate proteoglycan; Epican; CDw44 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 5 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
產(chǎn)品文獻(xiàn) ： |
[1] Su Y et al. 2016. Cancer Med. 5(3): 558-73. PMID 26775583. [2] Thompson SM et al. 2014. Cardiovasc Intervent Radiol. doi: 10.1007/s0027-013-0828-3. PMID 24452318. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/cd44-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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