| 克隆類型 ： |
Mouse Polyclonal Antibody |
|
亞 型 ： |
Mouse Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Pyruvate Kinase M2. |
|
產(chǎn)品描述 ： |
PKM2 is a glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP for generating ATP. There are 4 isoenzymes of pyruvate kinase in mammals (L, R, M1 and M2) encoded by 2 different genes: PKLR and PKM. The L and R isoenzymes are generated from the PKLR by differential splicing of RNA; the M1 and M2 forms are produced from the PKM gene by differential splicing. L type is the major isozyme in liver, R is found in red cells, M1 is the main form in muscle, heart and brain, and M2 is found in early fetal tissues as well as in most cancer cells. This antibody binds to both M1 and M2 isoforms of PKM. |
| 適用物種 ： |
H, M, R, Rb |
|
應(yīng)用范圍 ： |
E, WB, IHC |
| 應(yīng)用說明 ： |
E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500 |
| 別 名 ： |
Pyruvate kinase isozymes M1/M2; Pyruvate kinase muscle isozyme; Pyruvate kinase 2/3; Cytosolic thyroid hormone-binding protein; CTHBP; THBP1; PKM2; PK2; PK3; PKM1; M1-PK; M2-PK |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/pyruvate-kinase-m2-antibody |
| 標 記 物 ： |
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產(chǎn)品說明 ： |
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