| 克隆類型 ： |
Rabbit Polyclonal Antibody, Modification Specific Antibody, Biotin-conjugated Antibody |
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亞 型 ： |
Rabbit Ig |
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免 疫 原 ： |
Acetylated KLH-conjugates |
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產(chǎn)品描述 ： |
DNA transcription cannot take place unless DNA is unwound from the nucleosomes. The cell unwinds DNA by acetylation of lysine residues of histones. Research has shown that acetylation of non-histone proteins (e.g. transcription factors) and histones are involved in transcription. Histone acetyltransferases (HAT) acetylate the conserved amino-terminal domains of the four core histones (H2A, H2B, H3 and H4) on lysine residues, whereas histone deacetylases (HDAC) remove them. This pan-specific antibody recognizes proteins with acetyllysine residues. This antibody has been utilized for proteomic studies of protein acetylation, immunoaffinity chromatography separation and isolation of acetylated proteins and peptides from protease-digested whole cells.
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| 適用物種 ： |
H, M, R |
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應(yīng)用范圍 ： |
E, WB, IP, IHC |
| 應(yīng)用說明 ： |
Cat. No. 251116 has been tested on acetylated histones, acetylated BSA and acetylated MBP. There is no reaction with non-acetylated proteins. E: 1:500-1:2,000; WB: 1:200-1:1000; IHC: 1:100-1:500 |
| 別 名 ： |
Acetylated Lysine; AcK; Acetyllysine; Acetyl-lysine; AcLys |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.4 ml (0.25 mg/ml) of PBS pH7.4, 50% glycerol. Antibody was purified by using acetyllysine-affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/acetylated-lysine-antibody-1 |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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