| 克隆類型 ： |
Mouse Monoclonal Antibody, PE-conjugated Antibody |
|
亞 型 ： |
mouse IgG1 |
|
產(chǎn)品描述 ： |
The CD6 (HI210) Antibody recognizes a 100-130 kDa type-I single-chain transmembrane glycoprotein, a receptor for CD166. CD6 is expressed at low levels on immature thymocytes and at high levels on mature thymocytes. CD6 is also expressed at high levels on peripheral blood T cells and at low levels on most peripheral blood B cells. High levels of CD6 are present in T-cell malignancies and certain B-cell malignancies including B-CLL. CD6 not only is expressed on all CD5+ B-CLL, but also on CD5- B-CLL, suggesting a broader distribution of CD6 than CD5 in B-cell malignancies. CD6 has also been found recently to be expressed in a minor subset of myeloid malignancies. CD6 functions as an adhesion molecule as well as a costimulatory molecule for T cell activation. |
| 適用物種 ： |
H |
|
應(yīng)用范圍 ： |
FC |
| 應(yīng)用說(shuō)明 ： |
FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. E: 1:500-1:1,000; FC: 1:200-1:1,000; IHC: 1:200-1:500 |
| 別 名 ： |
T-cell differentiation antigen CD6; T12; TP120; CD6 antigen; CD6 |
|
形 態(tài) ： |
Each vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
|
產(chǎn)品文獻(xiàn) ： |
Schlossman S. et al., eds. 1995. Leucocyte Typing V: White Cell Differentiation Antigens. P246, Oxford University Press, New York. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/cd6-hi210-antibody-1 |
| 標(biāo) 記 物 ： |
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產(chǎn)品說(shuō)明 ： |
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