| 克隆類型 ： |
Mouse Monoclonal Antibody, FITC-conjugated Antibody |
|
亞 型 ： |
mouse IgM |
|
產(chǎn)品描述 ： |
The CD14 (HI221) antibody recognizes a 53-55 kDa glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein, which is found on cells of myelomonocytic lineage including monocytes (strongly), granulocytes (weakly) and also on most tissue macrophages. CD14 antigen is also present on reticular dendritic cells, some Langerhans cells, and B lymphocytes (weakly), but is absent from T lymphocytes, NK cells, erythrocytes and platelets. CD14 functions as a high affinity receptor for the complex of lipopolysaccharide (LPS-endotoxin) and LPS-binding protein (LBP), and is the major receptor involved in the lethal response to both endotoxin and Gram-negative bacteria. In addition to membrane CD14, soluble form of CD14 can be detected in serum and tissue culture supernatants of cells transfected with CD14. |
| 適用物種 ： |
H |
|
應(yīng)用范圍 ： |
FC |
| 應(yīng)用說明 ： |
FC with whole blood: 100 μl blood + 20 μl antibody; FC with cells: 10E6 cells + 20 μl antibody. FC: 1:200-1:1,000 |
| 別 名 ： |
Monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; Monocyte differentiation antigen CD14, urinary form; Monocyte fiferentiation antigen CD14, membrane-bound form; CD14 |
|
形 態(tài) ： |
Each vial contains 2 ml IgM (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by hydroxyapatite chromatography. |
| 保存條件 ： |
Store at 4°C. Product is guaranteed 6 months from the date of shipment. |
|
產(chǎn)品文獻(xiàn) ： |
Tadamitsu K. et al., eds. 1997. Leucocyte Typing VI: White Cell Differentiation Antigens. P49-52, 113-114 Garland Publishing, Inc., New York. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/cd14-hi221-antibody-0 |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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