| 克隆類型 ： |
Rabbit Polyclonal IgG |
|
免 疫 原 ： |
Peptide derived from human MLL5. |
|
純化方式 ： |
Immunogen affinity purified |
|
緩 沖 液 ： |
PBS, pH 7.4(1%BSA and 0.1% Sodium azide) |
|
產(chǎn)品描述 ： |
MLL5 is a divergent member of the Drosophila Trithorax related SET and PHD domain containing chromatin regulators that are involved in the regulation of transcriptional "memory" during differentiation. Human MLL5 is located on chromosome 7q22, that is frequently deleted in myeloid leukemias. Inactivation of the Mll5 gene in mice results in a reduction in the average representation of hematopoietic stem cells, and in functional impairment of long term hematopoietic repopulation potential under competitive conditions. Overexpression of the protein also inhibits cell cycle progression.This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a protein with an N-terminal PHD zinc finger and a central SET domain. Overexpression of the protein inhibits cell cycle progression. |
| 適用物種 ： |
Hu, Mo, Rat, Dog, Pig, Cow, Hor, Sheep |
| 應(yīng)用說明 ： |
WB: 1:200-1:1000 E: 1:500-1:1000 IHC: 1:200-1:1000 IF: 1:100-1:500 |
| 別 名 ： |
HDCMC04P; Histone lysine N methyltransferase MLL5; KMT2E; Lysine N methyltransferase 2E; Myeloid/lymphoid or mixed lineage leukemia 5 (trithorax homolog, Drosophila); Myeloid/lymphoid or mixed lineage leukemia 5; Myeloid/lymphoid or mixed lineage leukemia protein 5; MLL5_HUMAN. |
| 保存條件 ： |
Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted. |
| 標 記 物 ： |
PLLABS公司可供應(yīng)生物素、辣根過氧化物酶、熒光素標記抗體 |
|
產(chǎn)品說明 ： |
|
