克隆類(lèi)型 : |
Rabbit Polyclonal IgG |
免 疫 原 : |
PhosphoPeptide derived from Hu Acetyl Coenzyme A carboxylase alpha around the phosphorylation site of Ser78. |
純化方式 : |
Immunogen affinity purified |
緩 沖 液 : |
PBS, pH 7.4(1%BSA and 0.1% Sodium azide) |
產(chǎn)品描述 : |
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. |
適用物種 : |
Hu, Pig, Hor, |
應(yīng)用說(shuō)明 : |
E: 1:500-1:1000 IHC: 1:200-1:1000 IF: 1:100-1:500 |
別 名 : |
Acetyl Coenzyme A Carboxylase alpha (phospho S78); p-Acetyl Coenzyme A Carboxylase alpha (phospho S78); ACAC; ACACA; ACACA_Hu; ACC alpha; ACC; ACC1; ACCA; acetyl CoA carboxylase 1; acetyl Coenzyme A; Biotin carboxylase; Acetyl-Coenzyme A Carboxylase alpha. |
保存條件 : |
Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted. |
標(biāo) 記 物 : |
PLLABS公司可供應(yīng)生物素、辣根過(guò)氧化物酶、熒光素標(biāo)記抗體 |
產(chǎn)品說(shuō)明 : |
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