| 克隆類型 ： |
Rabbit Polyclonal IgG |
|
免 疫 原 ： |
PhosphoPeptide derived from Hu APP770 around the phosphorylation site of Thr743. |
|
純化方式 ： |
Immunogen affinity purified |
|
緩 沖 液 ： |
PBS, pH 7.4(1%BSA and 0.1% Sodium azide) |
|
產(chǎn)品描述 ： |
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). |
| 適用物種 ： |
Hu, Mo, Rat, Chi, Dog, Pig, Cow |
| 應用說明 ： |
WB: 1:200-1:1000 E: 1:500-1:1000 IHC: 1:200-1:1000 IF: 1:100-1:500 |
| 別 名 ： |
Amyloid Precursor Protein (phospho T743); Amyloid Precursor Protein (phospho Thr743); p-Amyloid Precursor Protein (phospho T743); APP (Phospho-Thr743); p-APP(Thr743); C31; C80; C83; C99; beta-amyloid precursor protein C-terminus; A4 amyloid protein; A4; AAA; ABETA; ABPP; AD1; Alzheimer disease 1; Alzheimer disease; Alzheimer's disease amyloid protein; Amyloid beta (A4) precursor protein; APP; APPI; Beta amyloid peptide; Cerebral vascular amyloid peptide; CTFgamma; CVAP; Hu mRNA for amyloid A4 precursor of Alzheimer's disease; PN II; PN2; PreA4; Protease nexin II; A4_Hu. |
| 保存條件 ： |
Store at -20°C for one year. Avoid repeated freeze-thaw cycles. At 4°C for 2-3 weeks after reconstituted. |
| 標 記 物 ： |
PLLABS公司可供應生物素、辣根過氧化物酶、熒光素標記抗體 |
|
產(chǎn)品說明 ： |
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