| 克隆類型 ： |
Mouse Monoclonal Antibody |
|
亞 型 ： |
mouse IgM |
|
產(chǎn)品描述 ： |
The CD57 (HI57a) antibody recognizes a 110-115 kDa carbohydrate antigen also called B3GAT1, HNK-1 and Leu7. CD57 antigen is expressed on 12-20% of normal peripheral blood lymphocytes including subsets of NK cells and CD8+ Ts/Tc. CD57 expression increases with age in peripheral blood lymphocytes to 25-40% in patients over 80 year-old. CD57 is not expressed by cord blood lymphocytes, B lymphocytes, monocytes, granulocytes, platelets and erythrocytes. CD57+ cell population increases in pathologies characterized by an imbalance of CD4/CD8 lymphocytes, e.g. AIDS, autoimmune diseases, allograft transplants, and viral infections. The CD57 molecule is shared by normal neural and striated muscle and their neoplastic counterparts including neurofibromas, neurofibrosarcomas and malignant melanomas. CD57 is also present on normal and neoplastic prostatic epithelia, where it represents a prognostic factor showing a positive correlation between the number of CD57+ cells and an increased survival of the neoplastic patients. |
| 適用物種 ： |
H |
|
應(yīng)用范圍 ： |
E, FC |
| 應(yīng)用說明 ： |
E: 1:500-1:1,000; FC: 1:200-1:1,000 |
| 別 名 ： |
Beta-1,3-glucuronyltransferase 1; Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1; Glucuronosyltransferase-P; GlcAT-P; UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase; GlcUAT-P; B3GAT1; GLCATP; HNK-1; HSO(3)-3GlcAbeta1-3Galbeta1-4GlcNAc-; Leu7; CD57 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
產(chǎn)品文獻(xiàn) ： |
Tadamitsu K. et al., eds. 1997. Leucocyte Typing VI: White Cell Differentiation Antigens. P49-52, 113-114 Garland Publishing, Inc., New York. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/cd57-hi57a-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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