| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human TGF-beta 1. |
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產(chǎn)品描述 ： |
The TGF-beta superfamily is composed of numerous growth differentiation factors, including transforming growth factor beta 1, 2 , and 3 (TGF-beta 1, TGF-beta 2 and, TGF-beta 3). TGF-beta 1 controls proliferation, differentiation and other functions in many cell types. TGF-beta 1 is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. The inactive form consists of a TGF-beta 1 homodimer non-covalently linked to a latency-associated peptide (LAP) homodimer. The active form is a disulfide-linked homodimer of mature TGF-beta 1. Defects in TGF-beta 1 are the cause of Camurati-Emgelmann disease, a progressive diaphyseal dysplasia characterized by hyperostosis ans sclerosis of the diaphyses of long bones. |
| 適用物種 ： |
H, M, R |
|
應(yīng)用范圍 ： |
E, WB, IHC |
| 應(yīng)用說明 ： |
Cat. No. 250876 does not react with TGF-beta 2 and TGF-beta 3. E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:200-1:500 |
| 別 名 ： |
Transforming growth factor beta-1; TGF-beta-1; TGFB1; TGFB; Latency-associated peptide; LAP |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
產(chǎn)品文獻(xiàn) ： |
Sano M et al. 2014. PLos One. 20;9(3):e89830. PMID#24651519. |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/tgf-beta-1-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說明 ： |
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