| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PLGF. |
|
產品描述 ： |
Placenta growth factor (PLGF or PIGF) is a dimeric glycoprotein showing the highest degree of sequence similarity to the vascular endothial growth factor. Alternative splicing of the PLGF primary transcript gives rise to three forms named PIGF-1, 2 and 3, which differ only in the insertion of a highly basic 21-amino acid stretch at the carboxyl end. PLGF is active in angiogenesis and endothelial cell growth by stimulating their proliferation and migration. PLGF binds to receptor VEGFR-1/FLT1. PLGF-2 binds neuropilin-1 and 2 in a heparin-dependent manner. Whereas the three forms are present in most placental tissues, PIGF-2 is specific to early (8 week) placenta and only PIGF-1 is found in the colon and mammary carcinomas. |
| 適用物種 ： |
H, M, R |
|
應用范圍 ： |
E, WB, IHC |
| 應用說明 ： |
E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500 |
| 別 名 ： |
Placenta growth factor; PIGF; PGFL; PLGF; PGF |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 0.1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A and immunogen affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
產品文獻 ： |
[1] Wu MY et al. 2013. European Journal of Pharmacology. doi: 10.1016/j.ejphar.2013.07.010. PMID# 23872401. [2] Tu H et al. 2013. Journal of Cellular Physiology. Research Article. 228(5):983-990. PM |
| 產品鏈接 ： |
http://www.abbiotec.com/antibodies/plgf-antibody |
| 標 記 物 ： |
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產品說明 ： |
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