| 克隆類型 ： |
Rabbit Polyclonal Antibody |
|
亞 型 ： |
Rabbit Ig |
|
免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human GLUT2. |
|
產(chǎn)品描述 ： |
Glucose transporter type 2 (GLUT2 or SLC2A2) is a facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells. GLUT2 is also part of the glucose-sensing mechanism of the beta cell and participate with the Na+/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. Defects in GLUT2 are the cause of Fanconi-Bickel syndrome, characterized by hepatorenal glycogen accumulation, proximal renal tubular dysfunction, and impaired utilization of glucose and galactose. |
| 適用物種 ： |
H, M, Mk, R, P |
|
應(yīng)用范圍 ： |
E, WB, IHC |
| 應(yīng)用說明 ： |
E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500 |
| 別 名 ： |
Solute carrier family 2 facilitated glucose transporter member 2; Glucose transporter type 2 liver; GLUT-2; SLC2A2; GLUT2 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
|
產(chǎn)品文獻 ： |
[1] Kosfeld A. et al. 2015. Department of Human Genetics, OE 6300, Hannover Medical School. Jan;135(1):69-87. PMID: 26572137. [2] Nakayama T. et al. 2010. Am. J. Physiol. Renal Physiol. 298: F712-F720 |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/glut2-antibody |
| 標 記 物 ： |
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產(chǎn)品說明 ： |
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