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GAP-43 Antibody

產(chǎn)品名稱 ： GAP-43 Antibody

中文名稱 ：

產(chǎn)品類別 ：一抗

品　　牌 ： ABBIOTEC

貨　　號 ： 250658

規(guī)　　格 ： 0.1mg

詳細(xì)信息

克隆類型：	Rabbit Polyclonal Antibody
亞　　型：	Rabbit Ig
免疫原：	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human GAP-43.
產(chǎn)品描述：	GAP-43 (Growth associated protein-43, neuromodulin) is a cytoplasmic axonal membrane protein that is involved in the neuronal outgrowth and synaptic plasticity of developing and regenerating neurons . Palmitoylated GAP-43 attaches to the membrane via lipid rafts, while the unmodified form is a component of the centrosome. GAP-43 binds to calmodulin in the absence of Ca++ and functions as a substrate for PKC in the nerve growth factor (NGF) signaling pathway. Gap-43 functions as an adapter protein, binding and interacting with several molecules including PKC, PIP2, actin, calmodulin, spectrin, palmitate, synaptophysin, amyloid, and tau. A lack of GAP-43 or phosphorylation leads to severe neuronal developmental or learning disfunction.
適用物種：	H, M, R, B, Ck
應(yīng)用范圍：	E, WB, IHC
應(yīng)用說明：	E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
別　　名：	GAP-43; Growth-associated protein 43; Neuromodulin; Axonal membrane protein GAP-43; PP46; Neural phosphoprotein B-50; GAP43
形　　態(tài) ：	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
保存條件：	Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
產(chǎn)品鏈接：	http://www.abbiotec.com/antibodies/gap-43-antibody
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產(chǎn)品說明：

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