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克隆類(lèi)型：	Rabbit Polyclonal Antibody
亞　　型：	Rabbit Ig
免疫原：	KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human EGFR.
產(chǎn)品描述：	Epidermal growth factor receptor (EGFR) is a receptor for EGF and for various members of the EGF family such as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. EGFR is involved in the control of cell growth and differentation. Binding of EGF to the receptor leads to dimerization, internalization of the EGF-receptor complex, induction of the tyrosine kinase activity, stimulation of cell DNA synthesis and cell proliferation. Defects in EGFR are associated with lung cancer.
適用物種：	H, M, R
應(yīng)用范圍：	E, WB, IHC
應(yīng)用說(shuō)明：	E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:200-1:500
別　　名：	Epidermal growth factor receptor; receptor tyrosine-protein kinase ErbB-1; EGFR; ERBB1
形　　態(tài) ：	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
保存條件：	Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
產(chǎn)品文獻(xiàn) ：	Deng J et al. 2013. Tumor Biology. 34(5):2791-800. PMID# 23824569.
產(chǎn)品鏈接：	http://www.abbiotec.com/antibodies/egfr-antibody
標(biāo) 記物：
產(chǎn)品說(shuō)明：

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