| 克隆類(lèi)型 ： |
Rabbit Polyclonal Antibody |
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亞 型 ： |
Rabbit Ig |
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免 疫 原 ： |
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human PECAM1. |
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產(chǎn)品描述 ： |
CD31 (PECAM1) is a member of the immunoglobulin (Ig) superfamily that is expressed on the surface of circulating platelets, monocytes, neutrophils, and particular T-cell subsets. CD31 is also a major constituent of the endothelial cell intercellular junction, where up to an estimated 1 million molecules are concentrated. Because of this cellular expression pattern, CD31 is implicated in several functions, including transendothelial migration of leukocytes, angiogenesis, and integrin activation. Ig superfamily members are known to mediate cell adhesion, or antigen recognition, e.g. immunoglobulins, T-cell receptors, and MHC molecules. In addition, a subgroup comprising 30 members characterized by the presence of one or more immunoreceptor tyrosine-based inhibitory motifs (ITIMs) within their cytoplasmic domain has also been recognized. CD31, which has 6 ITIMs within its cytoplasmic domain, is a member of this subfamily. CD31 is often used as a marker of the vascular endothelium. |
| 適用物種 ： |
H, M, B, P, Sh |
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應(yīng)用范圍 ： |
E, WB, IHC, IP, IF |
| 應(yīng)用說(shuō)明 ： |
E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:200-1:500 |
| 別 名 ： |
Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; CPIIA'; CD31 antigen; PECAM1 |
|
形 態(tài) ： |
Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography. |
| 保存條件 ： |
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
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產(chǎn)品文獻(xiàn) ： |
[1] Hogan M et al. 2016. Aims Bioengineering. 3(3): 277-88. [2] Florida SE et al. 2016. Connect Tissue Res. PMID 27184487. [3] Huang H et al. 2016. J Neuroinflammation. PMID 27586239. [4] Hall A. et a |
| 產(chǎn)品鏈接 ： |
http://www.abbiotec.com/antibodies/cd31-antibody |
| 標(biāo) 記 物 ： |
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產(chǎn)品說(shuō)明 ： |
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深圳市豪地華拓生物科技有限公司