產(chǎn)品說明 :
產(chǎn)品貨號Reference: CAN-LH-4040
檢測方法Kit Type: Sandwich ELISA
規(guī)格Kit Size: 96-well break-apart microplate
靈敏度Sensitivity: 0.2 IU/L
檢測樣本Sample Type: Human serum / 25 μL
檢測范圍Calibrator Range: 1–100 IU/L
檢測時間Total Assay Time: 80 minutes
背景介紹:
人促黃體生成素(HLH)是一種由垂體前葉合成的糖蛋白。這種激素由兩個亞基組成:α和β。LH的α亞單位與hCG的α亞單位(由胎盤產(chǎn)生)相似,都存在于促卵泡激素和促甲狀腺激素糖蛋白激素(也是由垂體合成的)和人絨毛膜促性腺激素的α亞單位(也是由垂體合成的)中。然而,每種激素的β亞基都是獨一無二的。因此,這四種激素的特異性是由β肽鏈決定的。值得注意的是α鏈本身沒有生物活性。
Human luteinizing hormone (hLH) is a glycoprotein synthesized by the anterior lobe of the pituitary gland. This hormone consists of two subunits: α and β. The α subunit of LH is similar to the α subunit found in both the FSH and TSH glycoprotein hormones (which are also synthesized by the pituitary gland) as well as the α subunit of hCG (produced by the placenta). However, the β subunit of each of these hormones are unique. Therefore, the specificity of these four hormones are due to the β peptide chains. It is to be noted that the α chain by itself has no biological activity.