產(chǎn)品說明 :
產(chǎn)品貨號Reference: CAN-HCG-4120
檢測方法Kit Type: Sandwich ELISA
規(guī)格Kit Size: 96-well break-apart microplate
靈敏度Sensitivity: 0.7 IU/L
檢測樣本Sample Type: Human serum / 25 μL
檢測范圍Calibrator Range: 2.5–500 IU/L
檢測時間Total Assay Time: 75 minutes
背景介紹:
人絨毛膜促性腺激素(HCG)是胎盤分泌的一種糖蛋白激素。在正常妊娠期間,血清和尿液中的這種激素水平逐漸升高,直到懷孕8周左右。HCG有兩個亞基,即α和β。α亞單位類似于垂體前葉糖蛋白激素的α亞單位,即LH、促甲狀腺激素和促卵泡激素。然而,這些激素的β亞基是不同的。因此,這種獨特性將一種激素與另一種激素區(qū)分開來,從而產(chǎn)生特異性。在制備這種單克隆抗體時,所用的免疫原是βhCG,這有助于使DBC檢測系統(tǒng)具有很高的特異性和敏感性。
Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by the placenta. During normal pregnancy the level of this hormone in serum and urine gradually increases up to about the eighth week of pregnancy. hCG has two subunits, namely α and β. The α subunit is similar to the α subunit of the anterior pituitary gland glycoprotein hormones, namely, LH, TSH and FSH. However, the β subunits of these hormones are different. Therefore, this uniqueness distinguishes one hormone from the other, hence specificity. In raising this monoclonal antibody, the immunogen used was βhCG, which helps to make the DBC assay system very specific and sensitive.