產(chǎn)品貨號Reference:             CAN-AD-208
檢測方法Kit Type:                Competitive ELISA
規(guī)格Kit Size:                         96-well break-apart microplate
靈敏度Sensitivity:                 0.04 ng/mL
檢測樣本Sample Type:          Human serum / 25 μL
檢測范圍Calibrator Range:   0.1–10 ng/mL
檢測時間Total Assay Time:   80 minutes

背景介紹：

雄烯二酮是由腎上腺和性腺產(chǎn)生的。因此，血清中雄烯二酮水平的測定對評價這些腺體的功能狀態(tài)具有重要意義。雄烯二酮是睪酮和雌酮的前體。在女性中除了腎上腺外，卵巢也是雄烯二酮的重要來源。據(jù)報道，雄烯二酮在排卵周期中呈逐日波動的趨勢。女性睪酮的主要產(chǎn)生來自于其他相關(guān)雄激素的轉(zhuǎn)化，尤其是雄烯二酮。女性睪丸激素水平異常應(yīng)伴有血清雄烯二酮水平的測定。血清睪酮的測定與雄烯二酮的酶免疫測定相結(jié)合，可用來確定雄激素過量產(chǎn)生的來源是腎上腺還是卵巢。
Androstenedione is produced by the adrenals and gonads. As a result, the determination of the level of androstenedione in serum is important in the evaluation of the functional state of these glands. Androstenedione is a precursor of testosterone and estrone. Besides the adrenals, in females, the ovaries have been shown to be an important source of androstenedione. It has been reported that there is a fluctuation day by day of androstenedione during the ovulatory cycle.The principle production of testosterone in females is from the conversion of other related androgens, especially androstenedione. An abnormal testosterone level in women should be accompanied by the estimation of serum androstenedione. The use of serum testosterone determination in conjunction with the enzyme immunoassay of androstenedione can be used to determine if the source of the excess androgen production is adrenal or ovarian.