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序 列 ： The synthetic peptide used to raise the antibody Cat. No. 250880 is selected from a sequence within the N-term region of human TGFR2. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended. |
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分 子 量 ： 1454.6 g/mol |
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純 度 ：Purity > 80% by HPLC
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形 態(tài) ：Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
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溶 解： Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile. |
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保存條件 ：Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C. |
| 別 名 ：TGF-beta receptor type-2; Transforming growth factor-beta receptor type II; TGF-beta receptor type II; TGF-beta type II receptor; TbetaR-II; TGFR-2; TGFBR2 |
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產(chǎn)品描述 ：TGF-beta receptor type II (TGFR2) forms a heteromeric complex with TGFR1 after binding TGF-beta at the cell surface and activates TGFR2 by phosphorylation, subsequently binding and activation of the SMAD transcriptional regulators. Defects in TGFR2 are a cause of hereditary non-polyposis colorectal cancer type 6 (HNPCC6), esophageal cancer, and Loeys-Dietz syndromes (aortic aneurism syndrome). |
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產(chǎn)品鏈接 ：http://www.ABBIOTEC.com/peptides/tgf-beta-receptor-type-ii-peptide
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